Scientists grow ‘mini-brain on the move’ that can contract muscle

Scientists have grown a miniature brain in a dish with a spinal cord and muscles attached, an advance that promises to accelerate the study of conditions such as motor neurone disease.

The lentil-sized grey blob of human brain cells were seen to spontaneously send out tendril-like connections to link up with the spinal cord and muscle tissue, which was taken from a mouse. The muscles were then seen to visibly contract under the control of the so-called brain organoid.

The research is is the latest in a series of increasingly sophisticated approximations of the human brain grown in the laboratory – this time with something approaching a central nervous system attached.

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